Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960364 | 1.00 | BRD4 (0.37) | BRD4CREBBPTSHRNPSR1PDCD1 | |
| SCHEMBL8960384 | 1.00 | BRD4 (0.37) | BRD4CREBBPTSHRNPSR1PDCD1 | |
| SCHEMBL23298307 | 0.81 | IRAK4 (0.33) | PDCD1CD274IRAK4MAPT | |
| SCHEMBL5213404 | 0.81 | PRKCA (0.37) | CREBBPPDCD1CD274PRKCAIRAK4 | |
| SCHEMBL5213410 | 0.81 | PRKCA (0.37) | CREBBPPDCD1CD274PRKCAIRAK4 | |
| SCHEMBL23298310 | 0.81 | IRAK4 (0.33) | PDCD1CD274IRAK4MAPT | |
| SCHEMBL1387675 | 0.81 | PRKCA (0.37) | CREBBPPDCD1CD274PRKCAIRAK4 | |
| SCHEMBL16187705 | 0.77 | BRD4 (0.36) | BRD4CREBBPPDCD1CD274PRKCA | |
| SCHEMBL21241285 | 0.77 | BRD4 (0.36) | BRD4CREBBPALDH1A1L3MBTL1IRAK4 | |
| SCHEMBL21241478 | 0.77 | BRD4 (0.36) | BRD4CREBBPALDH1A1L3MBTL1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-H08508991-A | — | — | 1996-09-24 | — | — | JP | claimed |
| EP-0693058-A1 | IMPROVEMENTS IN OR RELATING TO CHIRAL AUXILIARIES | OXFORD ASYMMETRY LIMITED (GB) | 1996-01-24 | — | — | EP | claimed |
| WO-1994024104-A1 | IMPROVEMENTS IN OR RELATING TO CHIRAL AUXILIARIES | OXFORD ASYMMETRY LIMITED (GB) | 1994-10-27 | — | — | WO | claimed |