Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13866874 | 0.83 | DPP4 (0.42) | DPP4CHRNB2ADRA1DHTR1ECHRNA3 | |
| SCHEMBL13875751 | 0.83 | HRH4 (0.51) | DPP4CHRNB2ADRA1DHTR1ECHRNA3 | |
| SCHEMBL13875671 | 0.81 | DPP4 (0.38) | DPP4CHRNB2ADRA1DHTR1ECHRNA3 | |
| SCHEMBL13875841 | 0.81 | DPP4 (0.38) | DPP4CHRNB2ADRA1DHTR1ECHRNA3 | |
| SCHEMBL13875837 | 0.81 | DPP4 (0.38) | DPP4CHRNB2ADRA1DHTR1ECHRNA3 | |
| SCHEMBL13875848 | 0.81 | ADRB1 (0.41) | DPP4CHRNB2ADRA1DHTR1ECHRNA3 | |
| SCHEMBL13875846 | 0.78 | TLR7 (0.41) | DPP4CHRNB2ADRA1DHTR1ECHRNA3 | |
| SCHEMBL13875749 | 0.78 | DPP4 (0.39) | DPP4CHRNB2ADRA1DHTR1ECHRNA3 | |
| SCHEMBL13875849 | 0.78 | DPP4 (0.39) | DPP4CHRNB2ADRA1DHTR1ECHRNA3 | |
| Trifluoroacetic Acid SCHEMBL3877706 | 0.77 | DPP4 (0.39) | DPP4CHRNB2ADRA1DHTR1ECHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |