Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | FAP | Q12884 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13866851 | 0.88 | DPP4 (0.57) | DPP4FAP | |
| SCHEMBL13875834 | 0.82 | DPP4 (0.46) | DPP4POLBCYP2C9CYP2C19L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL3885858 | 0.81 | DPP4 (0.49) | DPP4FAP | |
| SCHEMBL13866862 | 0.79 | DPP4 (0.57) | DPP4FAP | |
| SCHEMBL13866841 | 0.76 | DPP4 (0.59) | DPP4FAP | |
| SCHEMBL13875849 | 0.76 | DPP4 (0.39) | DPP4POLB | |
| SCHEMBL13866858 | 0.76 | DPP4 (0.53) | DPP4FAP | |
| SCHEMBL13866946 | 0.75 | DPP4 (0.43) | DPP4FAP | |
| SCHEMBL13866847 | 0.74 | DPP4 (0.56) | DPP4FAP | |
| SCHEMBL13866853 | 0.74 | DPP4 (0.62) | DPP4FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524847-B2 | Fused 1,3-dihydro-imidazole ring compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |