Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | CCKBR | P32239 | 5/20 | 0.63 |
| ▸ | CCKAR | P32238 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1387691 | 1.00 | CYP3A4 (0.63) | CYP3A4MAPTTSHRCCKBRCCKAR | |
| SCHEMBL1387571 | 0.89 | CCKAR (0.76) | CCKBRCCKAR | |
| SCHEMBL1387570 | 0.89 | CCKAR (0.76) | CCKBRCCKAR | |
| SCHEMBL9056654 | 0.88 | CCKAR (0.64) | CYP3A4MAPTTSHRCCKBRCCKAR | |
| SCHEMBL9091045 | 0.87 | CCKBR (0.82) | CYP3A4MAPTTSHRCCKBRCCKAR | |
| SCHEMBL9091207 | 0.83 | CCKBR (0.85) | CYP3A4MAPTTSHRCCKBRCCKAR | |
| SCHEMBL9091394 | 0.82 | CCKBR (0.77) | CYP3A4MAPTTSHRCCKBRCCKAR | |
| SCHEMBL9089077 | 0.82 | CCKBR (0.79) | CYP3A4MAPTTSHRCCKBRCCKAR | |
| SCHEMBL9091406 | 0.81 | CCKBR (0.84) | CYP3A4MAPTTSHRCCKBRCCKAR | |
| SCHEMBL9232391 | 0.81 | CCKBR (0.68) | CYP3A4MAPTTSHRCCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-H09504005-A | — | — | 1997-04-22 | — | — | JP | claimed |
| EP-0715624-A1 | PROCESS FOR THE PREPARATION OF BENZODIAZEPINE COMPOUNDS USEFUL AS ANTAGONISTS OF CCK OR OF GASTRINE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-06-12 | — | — | EP | claimed |
| WO-1995006040-A1 | BENZODIAZEPINE COMPOUNDS USEFUL AS ANTAGONISTS OF CCK OR OF GASTRINE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1995-03-02 | — | — | WO | claimed |
| EP-0715624-B1 | PROCESS FOR THE PREPARATION OF BENZODIAZEPINE COMPOUNDS USEFUL AS ANTAGONISTS OF CCK OR OF GASTRINE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-04-08 | — | — | EP | disclosed |
| US-5728829-A | MULTISTAGE REACTION OF N-PROTECTED BENZOTRIAZOLYL GLYCINE DERIVATIVE WITH AMINOKETONE, THEN REACTION WITH AMMONIA AND ACID CATALYZED CYCLIZATION | FERRING-RESEARCH LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |
| EP-0715624-A1 | PROCESS FOR THE PREPARATION OF BENZODIAZEPINE COMPOUNDS USEFUL AS ANTAGONISTS OF CCK OR OF GASTRINE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-06-12 | — | — | EP | disclosed |
| WO-1995006040-A1 | BENZODIAZEPINE COMPOUNDS USEFUL AS ANTAGONISTS OF CCK OR OF GASTRINE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1995-03-02 | — | — | WO | disclosed |