Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1387723 | 0.86 | AR (0.73) | ARPGR | |
| SCHEMBL1712475 | 0.82 | AR (1.00) | ARPGR | |
| SCHEMBL10327266 | 0.82 | AR (1.00) | ARPGR | |
| SCHEMBL10327487 | 0.82 | AR (1.00) | ARPGR | |
| SCHEMBL3489730 | 0.82 | AR (0.83) | ARPGR | |
| SCHEMBL629858 | 0.81 | AR (1.00) | ARPGR | |
| SCHEMBL632960 | 0.81 | AR (0.73) | ARPGR | |
| SCHEMBL1387702 | 0.80 | AR (0.74) | ARPGR | |
| SCHEMBL1773994 | 0.80 | AR (0.74) | ARPGR | |
| Acetic Acid SCHEMBL7784177 | 0.79 | AR (0.89) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738263-B1 | SUBSTITUTED PHENYLIMIDAZOLIDINES HAVING ANTIANDROGEN ACTIVITY | AVENTIS PHARMA SA (FR) | 2001-04-04 | — | — | EP | claimed |
| US-5750553-A | ANTIANDROGENIC AGENTS | ROUSSEL UCLAF (FR) | 1998-05-12 | — | — | US | claimed |
| JP-H09507241-A | — | — | 1997-07-22 | — | — | JP | claimed |
| EP-0738263-A1 | NOVEL OPTIONALLY SUBSTITUTED PHENYLIMIDAZOLIDINES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION, THEIR USE AS DRUGS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL UCLAF (FR) | 1996-10-23 | — | — | EP | claimed |
| WO-1995018794-A1 | NOVEL OPTIONALLY SUBSTITUTED PHENYLIMIDAZOLIDINES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION, THEIR USE AS DRUGS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL UCLAF (FR) | 1995-07-13 | — | — | WO | claimed |
| EP-0704448-B1 | Heterocyclic substituted imidazolidines, process and intermediates for their preparation, their use as medicaments and pharmaceutical compositions containing them | AVENTIS PHARMA SA (FR) | 2001-12-05 | — | — | EP | disclosed |
| EP-0738263-B1 | SUBSTITUTED PHENYLIMIDAZOLIDINES HAVING ANTIANDROGEN ACTIVITY | AVENTIS PHARMA SA (FR) | 2001-04-04 | — | — | EP | disclosed |
| US-6087509-A | DERIVATIVES OF TRIFLUOROBENZONITRILES | HOECHST MARION ROUSSEL (FR) | 2000-07-11 | — | — | US | disclosed |
| US-5958936-A | FOR INDUCING ANTIANDROGENIC ACTIVITY IN WARM-BLOODED ANIMALS, INCLUDING HUMANS | HOECHST MARION ROUSSEL (FR) | 1999-09-28 | — | — | US | disclosed |
| US-5750553-A | ANTIANDROGENIC AGENTS | ROUSSEL UCLAF (FR) | 1998-05-12 | — | — | US | disclosed |
| US-5705654-A | ANTIANDROGENS | ROUSSEL UCLAF (FR) | 1998-01-06 | — | — | US | disclosed |
| US-5646172-A | Method of inducing antiandrogenic activity using imidazolidines substituted with a heterocycle | ROUSSEL UCLAF (FR) | 1997-07-08 | — | — | US | disclosed |
| EP-0738263-A1 | NOVEL OPTIONALLY SUBSTITUTED PHENYLIMIDAZOLIDINES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION, THEIR USE AS DRUGS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL UCLAF (FR) | 1996-10-23 | — | — | EP | disclosed |
| EP-0704448-A1 | Heterocyclic substituted imidazolidines, process and intermediates for their preparation, their use as medicaments and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1996-04-03 | — | — | EP | disclosed |
| WO-1995018794-A1 | NOVEL OPTIONALLY SUBSTITUTED PHENYLIMIDAZOLIDINES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION, THEIR USE AS DRUGS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL UCLAF (FR) | 1995-07-13 | — | — | WO | disclosed |