Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2953860 | 0.92 | MAPT (0.49) | MAPTMEN1KMT2AHSD17B10TSHR | |
| SCHEMBL2953862 | 0.92 | MAPT (0.49) | MAPTMEN1KMT2AHSD17B10TSHR | |
| SCHEMBL13290693 | 0.91 | MEN1 (0.52) | MAPTMEN1KMT2AHSD17B10TSHR | |
| SCHEMBL13290611 | 0.90 | KMT2A (0.44) | MAPTMEN1KMT2AHSD17B10TSHR | |
| SCHEMBL2949749 | 0.90 | MEN1 (0.44) | MAPTMEN1KMT2AHSD17B10TSHR | |
| SCHEMBL13290909 | 0.90 | POLB (0.54) | MAPTMEN1KMT2AHSD17B10TSHR | |
| SCHEMBL2949751 | 0.90 | MEN1 (0.44) | MAPTMEN1KMT2AHSD17B10TSHR | |
| SCHEMBL13290828 | 0.90 | MEN1 (0.45) | MAPTMEN1KMT2AHSD17B10TSHR | |
| SCHEMBL2952606 | 0.87 | WNT3 (0.38) | MAPTMEN1KMT2AHSD17B10TSHR | |
| SCHEMBL2952601 | 0.87 | WNT3 (0.38) | MAPTMEN1KMT2AHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514449-B2 | Fused furan compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-04-07 | — | — | US | disclosed |
| US-7514449-B2 | Fused furan compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-04-07 | — | — | US | disclosed |