Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMO | Q99835 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TAS2R8 | Q9NYW2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11569757 | 0.90 | GAA (0.57) | ALDH1A1GAACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13879452 | 0.89 | ALDH1A1 (0.54) | ALDH1A1GAACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13879411 | 0.86 | ALDH1A1 (0.52) | ALDH1A1GAACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13879473 | 0.83 | NR1H3 (0.51) | ALDH1A1GAACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13879459 | 0.81 | ALDH1A1 (0.61) | ALDH1A1GAACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13879400 | 0.77 | GRM2 (0.44) | ALDH1A1SMOCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11612591 | 0.76 | KMT2A (0.48) | ALDH1A1SMOGAAMEN1KMT2A | |
| SCHEMBL13879425 | 0.76 | ALDH1A1 (0.50) | ALDH1A1GAATAS2R8L3MBTL1MEN1 | |
| SCHEMBL13879503 | 0.75 | ALDH1A1 (0.77) | ALDH1A1GAALMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL11398860 | 0.74 | GAA (0.74) | ALDH1A1GAACYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | INTERMUNE, INC. | 2009-04-16 | — | — | US | disclosed |
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | INTERMUNE, INC. | 2009-04-16 | — | — | US | disclosed |
| WO-2007047146-A2 | INHIBITORS OF VIRAL REPLICATION | INTERMUNE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099186-A1 | INHIBITORS OF VIRAL REPLICATION | EIF2AK2, HAVCR2, RTF2 | ALDH1A1 1500/4885SMO 3178/4885GAA 463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.