Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13290972 | 0.90 | SMN1; SMN2 (0.48) | KMT2AMAPTTP53MEN1HSD17B10 | |
| SCHEMBL13291009 | 0.90 | KMT2A (0.44) | KMT2ANPC1RAB9ACASP3SENP7 | |
| SCHEMBL13291013 | 0.88 | MAPT (0.59) | KMT2AMAPTTP53MEN1HSD17B10 | |
| SCHEMBL13665080 | 0.85 | NPC1 (0.46) | KMT2ANPC1RAB9ACASP3SENP7 | |
| SCHEMBL13665082 | 0.85 | NPC1 (0.46) | KMT2ANPC1RAB9ACASP3SENP7 | |
| SCHEMBL13291008 | 0.85 | NPC1 (0.48) | KMT2ANPC1RAB9ACASP3SENP7 | |
| SCHEMBL13665078 | 0.84 | NPC1 (0.49) | KMT2ANPC1RAB9ACASP3SENP7 | |
| SCHEMBL13291016 | 0.84 | NPC1 (0.44) | KMT2ANPC1RAB9ACASP3SENP7 | |
| SCHEMBL13665066 | 0.83 | NPC1 (0.44) | KMT2ANPC1RAB9ACASP3SENP7 | |
| SCHEMBL13665049 | 0.83 | NPC1 (0.44) | KMT2ANPC1RAB9ACASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514449-B2 | Fused furan compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-04-07 | — | — | US | disclosed |
| US-7514449-B2 | Fused furan compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-04-07 | — | — | US | disclosed |