Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.47 |
| ▸ | MPL | P40238 | 4/20 | 0.42 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.42 |
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.42 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.42 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | SNCA | P37840 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13744288 | 0.86 | BRD4 (0.43) | PHLPP2MPLSENP2SENP1SUMO2 | |
| SCHEMBL14388769 | 0.79 | SLC7A11 (0.50) | MPLSENP2SENP1SUMO2SUMO1 | |
| SCHEMBL11138059 | 0.78 | PTPN1 (0.36) | PHLPP2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL11138056 | 0.78 | PTPN1 (0.36) | PHLPP2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL13743964 | 0.77 | BRD4 (0.44) | PHLPP2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL11670548 | 0.77 | PTPN1 (0.35) | PHLPP2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL11670541 | 0.77 | PTPN1 (0.35) | PHLPP2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL334052 | 0.77 | PHLPP2 (0.58) | PHLPP2MPLSENP2SENP1SUMO2 | |
| SCHEMBL110002 | 0.77 | PHLPP2 (0.58) | PHLPP2MPLSENP2SENP1SUMO2 | |
| SCHEMBL29566193 | 0.77 | PHLPP2 (0.58) | PHLPP2MPLSENP2SENP1SUMO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090098074-A1 | Keratin-Binding Effector Molecules Containing Reactive Dyes | BASF SE (DE) | 2009-04-16 | — | — | US | disclosed |
| US-20090098074-A1 | Keratin-Binding Effector Molecules Containing Reactive Dyes | BASF SE (DE) | 2009-04-16 | — | — | US | disclosed |
| WO-2007063024-A2 | KERATIN-BINDING EFFECTOR MOLECULES CONTAINING REACTIVE DYES | BASF SE (DE) | 2007-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090098074-A1 | Keratin-Binding Effector Molecules Containing Reactive Dyes | KRT18, KLK3, KLKB1 | PHLPP2 1011/4885MPL 4870/4885SENP2 3702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.