SCHEMBL110002

SCHEMBL110002

COc1ccccc1/N=N/c1cc(S(=O)(=O)O)c2ccccc2c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHLPP2 Q6ZVD8 1/20 0.58
MPL P40238 4/20 0.54
CYP1A2 P05177 2/20 0.51
SENP2 Q9HC62 4/20 0.51
SENP1 Q9P0U3 4/20 0.51
SUMO2 P61956 3/20 0.51
SUMO1 P63165 3/20 0.51
SENP7 Q9BQF6 3/20 0.51
SENP3 Q9H4L4 2/20 0.51
THRB P10828 3/20 0.50
HPGD P15428 3/20 0.48
MAPT P10636 3/20 0.48
MEN1 O00255 2/20 0.48
ALDH1A1 P00352 2/20 0.48
RECQL P46063 2/20 0.48
BLM P54132 2/20 0.48
KMT2A Q03164 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
KDM4E B2RXH2 1/20 0.48
TP53 P04637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29566193 1.00 PHLPP2 (0.58) PHLPP2MPLCYP1A2SENP2SENP1
SCHEMBL334052 1.00 PHLPP2 (0.58) PHLPP2MPLCYP1A2SENP2SENP1
SCHEMBL1435818 0.99 PHLPP2 (0.57) PHLPP2MPLCYP1A2SENP2SENP1
SCHEMBL1435811 0.99 PHLPP2 (0.57) PHLPP2MPLCYP1A2SENP2SENP1
SCHEMBL23787721 0.89 PHLPP2 (0.72) PHLPP2MPLCYP1A2SENP2SENP1
SCHEMBL29358163 0.87 THRB (0.68) PHLPP2CYP1A2THRBHPGDMAPT
SCHEMBL1435814 0.87 THRB (0.68) PHLPP2CYP1A2THRBHPGDMAPT
SCHEMBL11875466 0.86 HPGD (0.51) PHLPP2MPLCYP1A2SENP2SENP1
SCHEMBL27622823 0.83 SLC7A11 (0.62) PHLPP2MPLCYP1A2SENP2SENP1
SCHEMBL1423907 0.83 PHLPP2 (0.70) PHLPP2CYP1A2SENP2SENP1SUMO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 425 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1738800-B1 Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer OREAL (FR) 2010-06-09 EP claimed
EP-1738801-B1 Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid OREAL (FR) 2010-06-09 EP claimed
US-12533303-B2 Composition for the simultaneous bleaching and dyeing of keratin fibres and process using this composition L'OREAL (FR) 2026-01-27 US disclosed
US-20250381107-A1 COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION OREAL (FR) 2025-12-18 US disclosed
US-20250381106-A1 COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION OREAL (FR) 2025-12-18 US disclosed
US-20250375361-A1 COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION OREAL (FR) 2025-12-11 US disclosed
WO-2025132917-A1 PROCESS FOR DYEING THE HAIR USING A LIGHTENING COMPOSITION AND A DYEING COMPOSITION COMPRISING A DIRECT DYE, AN AROMATIC COMPOUND AND A HYDROXYLATED ALIPHATIC SOLVENT L'OREAL (FR) 2025-06-26 WO disclosed
US-20250195349-A1 COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION L'OREAL (FR) 2025-06-19 US disclosed
EP-4543401-A1 COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION L'OREAL (FR) 2025-04-30 EP disclosed
EP-4543399-A1 COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION L'OREAL (FR) 2025-04-30 EP disclosed
EP-4543398-A1 COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION L'OREAL (FR) 2025-04-30 EP disclosed
US-20040127692-A1 Composition for the dyeing of human keratinous fibres comprising a monocationic monoazo dye L'OREAL S.A. (FR) 2004-07-01 US disclosed
US-20040049859-A1 Enzyme composition for bleaching human keratinous fibres and bleaching method L'OREAL S.A. (FR) 2004-03-18 US disclosed
US-20040034944-A1 Bleaching composition for dyed keratinous fibers L'OREAL S.A. (FR) 2004-02-26 US disclosed
US-20040019981-A1 Direct dyeing composition for keratinous fibres comprising a cationic associative polyurethane L'OREAL S.A. (FR) 2004-02-05 US disclosed
US-20030159221-A1 Oxidation dyeing composition for keratinous fibres with a particular paraphenylene-diamine derivative and a particular direct dyeing agent L'OREAL S.A. (FR) 2003-08-28 US disclosed
US-20030152534-A1 Composition for dyeing keratin fibers comprising a particular aminosilicone L'OREAL S.A. (FR) 2003-08-14 US disclosed
US-20030140429-A1 Keratin fibre dyeing composition comprising a particular aminosilicone L'OREAL S.A. (FR) 2003-07-31 US disclosed
US-20030106169-A1 Composition for dyeing human keratin fibres, comprising a particular monocationic monoazo dye L'OREAL S.A. (FR) 2003-06-12 US disclosed
US-5595197-A HAIR DYE L'OREAL (FR) 1997-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030159221-A1 Oxidation dyeing composition for keratinous fibres with a particular paraphenylene-diamine derivative and a particular direct dyeing agent KRT18, CDC73, DAO PHLPP2 3484/4885MPL 4624/4885CYP1A2 183/4885
US-20030106169-A1 Composition for dyeing human keratin fibres, comprising a particular monocationic monoazo dye KRT18, TUBB3, TUBB1 PHLPP2 2801/4885MPL 4885/4885CYP1A2 746/4885
US-20040049859-A1 Enzyme composition for bleaching human keratinous fibres and bleaching method KRT18, COXFA4, LPO PHLPP2 2346/4885MPL 4881/4885CYP1A2 423/4885
US-12533303-B2 Composition for the simultaneous bleaching and dyeing of keratin fibres and process using this composition KRT18, CA12, CA7 PHLPP2 1742/4885MPL 4866/4885CYP1A2 1655/4885
US-20250381106-A1 COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION KRT18, VIM, MAP1LC3A PHLPP2 2620/4885MPL 4885/4885CYP1A2 1319/4885
US-20040127692-A1 Composition for the dyeing of human keratinous fibres comprising a monocationic monoazo dye KRT18, WNT3, DSG1 PHLPP2 3582/4885MPL 4885/4885CYP1A2 542/4885
US-20030152534-A1 Composition for dyeing keratin fibers comprising a particular aminosilicone KRT18, TUBB8, TUBA8 PHLPP2 3072/4885MPL 4885/4885CYP1A2 2584/4885
US-20040019981-A1 Direct dyeing composition for keratinous fibres comprising a cationic associative polyurethane KRT18, DSG1, FSCN1 PHLPP2 3332/4885MPL 4884/4885CYP1A2 2230/4885
US-20030140429-A1 Keratin fibre dyeing composition comprising a particular aminosilicone KRT18, TUBB3, TUBA3E PHLPP2 2903/4885MPL 4884/4885CYP1A2 2225/4885
US-20040034944-A1 Bleaching composition for dyed keratinous fibers KRT18, PRKDC, HKDC1 PHLPP2 1907/4885MPL 4884/4885CYP1A2 1928/4885
US-20250375361-A1 COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION KRT18, VIM, MAP1LC3A PHLPP2 2585/4885MPL 4885/4885CYP1A2 1639/4885
US-20250195349-A1 COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION KRT18, VIM, CKAP4 PHLPP2 2579/4885MPL 4885/4885CYP1A2 1472/4885
US-20250381107-A1 COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION KRT18, VIM, MAP1LC3A PHLPP2 2385/4885MPL 4885/4885CYP1A2 1382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.