SCHEMBL13880686

SCHEMBL13880686

CCN(c1cccc(S(=O)(=O)CCOS(=O)(=O)O)c1)c1nc(Cl)nc(Nc2ccc3c(O)c(/N=N/c4ccc(OC)cc4S(=O)(=O)O)c(S(=O)(=O)O)cc3c2)n1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ PRMT1 Q99873 3/20 0.49
▸ CARM1 Q86X55 1/20 0.49
▸ FUT8 Q9BYC5 1/20 0.41
▸ ENPP2 Q13822 10/20 0.39
▸ CD40 P25942 1/20 0.38
▸ CD40LG P29965 1/20 0.38
▸ PHLPP2 Q6ZVD8 1/20 0.33
▸ PRMT3 O60678 1/20 0.33
▸ EP300 Q09472 1/20 0.33
▸ PRMT6 Q96LA8 1/20 0.33
▸ MEN1 O00255 1/20 0.31
▸ NPC1 O15118 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ PAX8 Q06710 1/20 0.31
▸ KLF5 Q13887 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16389050 0.83 FUT8 (0.44) PRMT1CARM1FUT8ENPP2CD40
SCHEMBL13483285 0.82 FUT8 (0.42) PRMT1CARM1FUT8ENPP2MEN1
SCHEMBL13881078 0.82 PRMT1 (0.47) PRMT1CARM1FUT8ENPP2CD40
SCHEMBL13483284 0.81 ENPP2 (0.48) PRMT1CARM1FUT8ENPP2MEN1
SCHEMBL4166597 0.81 PRMT1 (0.69) PRMT1CARM1FUT8ENPP2CD40
SCHEMBL3697527 0.81 PRMT1 (0.69) PRMT1CARM1FUT8ENPP2CD40
SCHEMBL12965814 0.81 CD40 (0.39) PRMT1CARM1FUT8ENPP2CD40
SCHEMBL14388936 0.80 PRMT1 (0.56) PRMT1CARM1FUT8ENPP2CD40
SCHEMBL14004226 0.79 CA1 (0.39) FUT8KMT2A
SCHEMBL3692856 0.78 PRMT1 (0.55) PRMT1CARM1FUT8ENPP2CD40

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090098074-A1 Keratin-Binding Effector Molecules Containing Reactive Dyes BASF SE (DE) 2009-04-16 — — US disclosed
US-20090098074-A1 Keratin-Binding Effector Molecules Containing Reactive Dyes BASF SE (DE) 2009-04-16 — — US disclosed
WO-2007063024-A2 KERATIN-BINDING EFFECTOR MOLECULES CONTAINING REACTIVE DYES BASF SE (DE) 2007-06-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090098074-A1 Keratin-Binding Effector Molecules Containing Reactive Dyes KRT18, KLK3, KLKB1 PRMT1 1728/4885CARM1 4397/4885FUT8 2015/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback