Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 10/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CD40 | P25942 | 1/20 | 0.33 |
| ▸ | CD40LG | P29965 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13880953 | 0.97 | THRB (0.45) | THRBENPP2CYP1A2CD40CD40LG | |
| SCHEMBL13880758 | 0.97 | THRB (0.42) | THRBENPP2CYP1A2CD40CD40LG | |
| SCHEMBL13880807 | 0.94 | THRB (0.42) | THRBENPP2CYP1A2CD40CD40LG | |
| SCHEMBL14374473 | 0.94 | THRB (0.45) | THRBENPP2CYP1A2CD40CD40LG | |
| SCHEMBL13880906 | 0.94 | THRB (0.45) | THRBENPP2CYP1A2CD40CD40LG | |
| SCHEMBL13880932 | 0.93 | THRB (0.45) | THRBENPP2CD40CD40LGMEN1 | |
| SCHEMBL14374479 | 0.92 | THRB (0.45) | THRBENPP2CYP1A2CD40CD40LG | |
| SCHEMBL13880929 | 0.92 | THRB (0.43) | THRBENPP2CYP1A2CD40CD40LG | |
| SCHEMBL13880762 | 0.92 | THRB (0.42) | THRBENPP2CYP1A2CD40CD40LG | |
| SCHEMBL13880938 | 0.92 | THRB (0.43) | THRBENPP2CYP1A2MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090098074-A1 | Keratin-Binding Effector Molecules Containing Reactive Dyes | BASF SE (DE) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090098074-A1 | Keratin-Binding Effector Molecules Containing Reactive Dyes | KRT18, KLK3, KLKB1 | THRB 3581/4885ENPP2 3626/4885CYP1A2 4054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.