Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3666485 | 0.83 | CRBN (0.33) | GSK3AGSK3BCRBN | |
| SCHEMBL1203304 | 0.76 | CRBN (0.52) | GSK3AGSK3BCRBN | |
| SCHEMBL3672260 | 0.70 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL21755690 | 0.69 | GSK3A (0.47) | GSK3AGSK3BCRBN | |
| SCHEMBL3666481 | 0.68 | KDM4E (0.36) | — | |
| SCHEMBL30135929 | 0.68 | KDM4E (0.36) | — | |
| SCHEMBL1203575 | 0.68 | KDM4E (0.36) | — | |
| SCHEMBL3544001 | 0.68 | KDM4E (0.37) | — | |
| SCHEMBL3673443 | 0.67 | ALDH1A1 (0.35) | CRBN | |
| SCHEMBL4079840 | 0.66 | KDM4E (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009040556-A1 | PYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | CYCLACEL LIMITED (GB) | 2009-04-02 | — | — | WO | disclosed |