Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.43 |
| ▸ | PTPRS | Q13332 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | GPR18 | Q14330 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13882804 | 1.00 | PGR (0.46) | PGRPTPN1MAPTMEN1KMT2A | |
| SCHEMBL13882809 | 1.00 | PGR (0.46) | PGRPTPN1MAPTMEN1KMT2A | |
| SCHEMBL13882665 | 1.00 | PGR (0.46) | PGRPTPN1MAPTMEN1KMT2A | |
| SCHEMBL13882787 | 1.00 | PGR (0.46) | PGRPTPN1MAPTMEN1KMT2A | |
| SCHEMBL13882950 | 1.00 | PGR (0.46) | PGRPTPN1MAPTMEN1KMT2A | |
| SCHEMBL13883166 | 0.90 | PGR (0.46) | PGRPTPN1MAPTMEN1KMT2A | |
| SCHEMBL13883164 | 0.90 | PTPN1 (0.37) | PGRPTPN1MAPTMEN1KMT2A | |
| SCHEMBL13883168 | 0.90 | PTPN1 (0.36) | PGRPTPN1MAPTMEN1KMT2A | |
| SCHEMBL13882768 | 0.90 | PTPN1 (0.36) | PGRPTPN1MAPTMEN1KMT2A | |
| SCHEMBL13882824 | 0.89 | PTPN1 (0.36) | PGRPTPN1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009048559-A1 | MAXI-K CHANNEL BLOCKERS AND METHODS OF USE | MERCK & CO., INC. (US) | 2009-04-16 | — | — | WO | disclosed |