Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | SNCA | P37840 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | F9 | P00740 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2816401 | 0.92 | EPHX2 (0.42) | NAMPTMCHR1SNCAMAPTPOLB | |
| SCHEMBL2815271 | 0.79 | LMNA (0.40) | NAMPTMCHR1MAPTEPHX2TP53 | |
| SCHEMBL2815908 | 0.76 | EPHX2 (0.44) | NAMPTMCHR1EPHX2CNR1 | |
| SCHEMBL2812870 | 0.74 | EPHX2 (0.43) | MCHR1EPHX2 | |
| SCHEMBL2813625 | 0.73 | KMT2A (0.46) | NAMPTPOLBLMNA | |
| SCHEMBL2816965 | 0.73 | EPHX2 (0.53) | NAMPTMAPTEPHX2 | |
| SCHEMBL2819274 | 0.72 | EPHX2 (0.43) | NAMPTMCHR1MAPTPOLBEPHX2 | |
| SCHEMBL2817947 | 0.72 | HIF1A (0.48) | NAMPTMAPTEPHX2LMNA | |
| SCHEMBL17957269 | 0.71 | LMNA (0.42) | NAMPTMCHR1EPHX2TP53LMNA | |
| SCHEMBL2813899 | 0.71 | EPHX2 (0.46) | NAMPTMAPTEPHX2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009046804-A1 | IMIDAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2009-04-16 | — | — | WO | disclosed |