Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13106578 | 1.00 | DPP4 (0.31) | DPP4PREPFAPALDH1A1SMN1; SMN2 | |
| SCHEMBL13003441 | 0.81 | — | — | |
| SCHEMBL14254659 | 0.79 | CYP2D6 (0.46) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1991577 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2 | |
| SCHEMBL2587295 | 0.75 | CYP4F2 (0.45) | ALDH1A1 | |
| SCHEMBL3596666 | 0.75 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL3261975 | 0.75 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL31637322 | 0.75 | CYP4F2 (0.42) | ALDH1A1 | |
| SCHEMBL1710403 | 0.75 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL13888946 | 0.74 | EPHX2 (0.38) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517892-B2 | Ligands for monoamine receptors and transporters, and methods of use thereof | SEPRACOR INC. (US) | 2009-04-14 | — | — | US | disclosed |