Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.62 |
| ▸ | ADAMTS4 | O75173 | 5/20 | 0.50 |
| ▸ | MMP2 | P08253 | 7/20 | 0.48 |
| ▸ | MMP9 | P14780 | 4/20 | 0.48 |
| ▸ | MMP13 | P45452 | 3/20 | 0.48 |
| ▸ | MMP3 | P08254 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP7 | P09237 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SCN4A | P35499 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13889013 | 0.90 | NR3C1 (0.59) | NR3C1ADAMTS4MMP2MMP9MMP13 | |
| SCHEMBL4509097 | 0.88 | NR3C1 (0.59) | NR3C1ADAMTS4MMP2MMP9MMP13 | |
| SCHEMBL4515277 | 0.86 | NR3C1 (0.63) | NR3C1MMP2MMP9MMP13MMP3 | |
| SCHEMBL4506870 | 0.85 | NR3C1 (0.62) | NR3C1MMP2MMP9MMP13MMP3 | |
| SCHEMBL4518136 | 0.84 | NR3C1 (0.64) | NR3C1ALDH1A1SCN4ACYP1A2CYP3A4 | |
| SCHEMBL4503415 | 0.82 | NR3C1 (0.59) | NR3C1ADAMTS4MMP2MMP9MMP13 | |
| SCHEMBL4517989 | 0.82 | NR3C1 (0.59) | NR3C1MMP2MMP9MMP13MMP3 | |
| SCHEMBL13889014 | 0.82 | NR3C1 (0.62) | NR3C1SMN1; SMN2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL4516008 | 0.82 | NR3C1 (0.59) | NR3C1ADAMTS4MMP2MMP9MMP13 | |
| SCHEMBL4526843 | 0.82 | NR3C1 (0.59) | NR3C1ALDH1A1SMN1; SMN2SCN4ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090093485-A1 | Novel Sulphonamide Derivatives as Glucocorticoid Receptor Modulators for the Treatment of Inflammatory Diseases | ASTRAZENECA AB (SE) | 2009-04-09 | — | — | US | disclosed |
| US-20090093485-A1 | Novel Sulphonamide Derivatives as Glucocorticoid Receptor Modulators for the Treatment of Inflammatory Diseases | ASTRAZENECA AB (SE) | 2009-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093485-A1 | Novel Sulphonamide Derivatives as Glucocorticoid Receptor Modulators for the Treatment of Inflammatory Diseases | NR3C1, NR3C2, NR5A1 | NR3C1 1/4885ADAMTS4 3658/4885MMP2 4447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.