Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16088328 | 0.89 | SLC10A2 (0.63) | SLC10A2 | |
| SCHEMBL1388931 | 0.89 | SLC10A2 (0.63) | SLC10A2 | |
| SCHEMBL8805763 | 0.82 | SLC10A2 (0.54) | SLC10A2 | |
| Hydrochloric Acid SCHEMBL8204275 | 0.81 | SLC10A2 (0.54) | SLC10A2 | |
| SCHEMBL9961456 | 0.81 | SLC10A2 (0.77) | SLC10A2 | |
| SCHEMBL2457392 | 0.81 | SLC10A2 (0.77) | SLC10A2 | |
| SCHEMBL22285894 | 0.81 | SLC10A2 (0.77) | SLC10A2 | |
| SCHEMBL2457393 | 0.81 | SLC10A2 (0.77) | SLC10A2 | |
| SCHEMBL25060242 | 0.81 | SLC10A2 (0.72) | SLC10A2 | |
| SCHEMBL8799496 | 0.80 | SLC10A2 (0.55) | SLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-H10504035-A | — | — | 1998-04-14 | — | — | JP | claimed |
| EP-0775126-A1 | HYPOLIPIDEMIC 1,4-BENZOTHIAZEPINE-1,1-DIOXIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1997-05-28 | — | — | EP | claimed |
| WO-1996005188-A1 | HYPOLIPIDEMIC 1,4-BENZOTHIAZEPINE-1,1-DIOXIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-02-22 | — | — | WO | claimed |
| EP-0775126-B1 | HYPOLIPIDEMIC 1,4-BENZOTHIAZEPINE-1,1-DIOXIDES | WELLCOME FOUND (GB) | 2002-10-30 | — | — | EP | disclosed |
| EP-1203769-A1 | Hypolipidemic 1,4-benzothiazepine derivative | THE WELLCOME FOUNDATION LIMITED (GB) | 2002-05-08 | — | — | EP | disclosed |
| US-5910494-A | NOVEL COMPOUNDS THAT REDUCE THE ABSORPTION OF BILE ACIDS FROM THE INTESTINE; FOR PROPHYLAXIS AND TREATMENT OF HYPERLIPIDEMIC CONDITIONS, SUCH AS ATHEROSCLEROSIS | GLAXO WELLCOME INC. (US) | 1999-06-08 | — | — | US | disclosed |
| EP-0775126-A1 | HYPOLIPIDEMIC 1,4-BENZOTHIAZEPINE-1,1-DIOXIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005188-A1 | HYPOLIPIDEMIC 1,4-BENZOTHIAZEPINE-1,1-DIOXIDES | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-02-22 | — | — | WO | disclosed |