Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 4/20 | 0.69 |
| ▸ | CHRM2 | P08172 | 11/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13889230 | 0.88 | CCR3 (0.90) | CCR3CHRM2 | |
| SCHEMBL18840752 | 0.82 | CCR3 (1.00) | CCR3CHRM2 | |
| SCHEMBL16349463 | 0.81 | CCR3 (0.71) | CCR3CHRM2CYP2C9 | |
| SCHEMBL13389936 | 0.81 | CCR3 (0.71) | CCR3CHRM2CYP2C9 | |
| SCHEMBL13889079 | 0.77 | CCR3 (0.82) | CCR3CHRM2 | |
| SCHEMBL13389350 | 0.76 | CCR3 (0.81) | CCR3CHRM2 | |
| SCHEMBL13407642 | 0.76 | CCR3 (0.79) | CCR3CHRM2 | |
| SCHEMBL13389682 | 0.76 | CCR3 (0.79) | CCR3CHRM2 | |
| SCHEMBL31395273 | 0.76 | KMT2A (0.60) | CCR3CHRM2CYP2C9 | |
| SCHEMBL13389546 | 0.75 | CCR3 (0.78) | CCR3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725235-B1 | PIPERIDINE DERIVATIVES USEFUL AS CCR3 ANTAGONISTS | SCHERING CORP (US) | 2009-04-15 | — | — | EP | disclosed |