Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 10/20 | 0.71 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.42 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13389936 | 1.00 | CCR3 (0.71) | CCR3CHRM2CYP2C9TACR1MBTD1 | |
| SCHEMBL16349449 | 0.89 | CCR3 (0.90) | CCR3CHRM2 | |
| SCHEMBL13389623 | 0.89 | CCR3 (0.90) | CCR3CHRM2 | |
| SCHEMBL13407807 | 0.83 | CCR3 (1.00) | CCR3CHRM2 | |
| SCHEMBL13389201 | 0.83 | CCR3 (1.00) | CCR3CHRM2 | |
| SCHEMBL13889152 | 0.81 | CCR3 (0.69) | CCR3CHRM2CYP2C9 | |
| SCHEMBL13389931 | 0.80 | CCR3 (0.72) | CCR3 | |
| SCHEMBL16349433 | 0.80 | CCR3 (0.72) | CCR3 | |
| SCHEMBL13889079 | 0.74 | CCR3 (0.82) | CCR3CHRM2 | |
| SCHEMBL13407805 | 0.74 | CCR3 (0.83) | CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705153-B2 | Bipiperdine derivatives useful as CCR3 antagonists | SCHERING CORPORATION (US) | 2010-04-27 | — | — | US | disclosed |