Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | IL18 | Q14116 | 1/20 | 0.41 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.39 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13889297 | 0.78 | CYP19A1 (0.56) | CYP19A1LMNATTBK1TTBK2CYP11B1 | |
| SCHEMBL13895544 | 0.78 | CYP19A1 (0.59) | CYP19A1PARP15PARP10PARP2POLB | |
| SCHEMBL4376200 | 0.75 | CYP19A1 (0.60) | CYP19A1PARP15PARP10PARP2POLB | |
| SCHEMBL4480751 | 0.75 | CYP19A1 (0.56) | CYP19A1PARP15PARP10PARP2POLB | |
| SCHEMBL15584627 | 0.75 | CYP19A1 (0.56) | CYP19A1PARP15PARP10PARP2POLB | |
| SCHEMBL2707449 | 0.75 | CYP19A1 (0.56) | CYP19A1PARP15PARP10PARP2POLB | |
| SCHEMBL8852392 | 0.74 | PARP15 (0.63) | CYP19A1PARP15PARP10PARP2POLB | |
| SCHEMBL7041250 | 0.74 | PARP15 (0.63) | CYP19A1PARP15PARP10PARP2POLB | |
| SCHEMBL15006214 | 0.71 | CYP19A1 (0.51) | CYP19A1PARP15PARP10PARP2POLB | |
| SCHEMBL8238126 | 0.70 | PARP15 (0.51) | CYP19A1PARP15PARP10PARP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517992-B2 | Non-nucleoside reverse transcriptase inhibitors | MEDIVIR AB (SE) | 2009-04-14 | — | — | US | disclosed |