SCHEMBL7041250

SCHEMBL7041250

N#Cc1ccc(Oc2ccc(C#N)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PARP15 Q460N3 1/20 0.63
▸ PARP10 Q53GL7 1/20 0.63
▸ PARP2 Q9UGN5 1/20 0.63
▸ KDM4E B2RXH2 2/20 0.61
▸ LMNA P02545 2/20 0.61
▸ CYP19A1 P11511 1/20 0.61
▸ MEN1 O00255 1/20 0.61
▸ POLB P06746 1/20 0.61
▸ MAPT P10636 1/20 0.61
▸ PKM P14618 1/20 0.61
▸ MAPK1 P28482 1/20 0.61
▸ RAB9A P51151 1/20 0.61
▸ KMT2A Q03164 1/20 0.61
▸ IL18 Q14116 1/20 0.61
▸ CA2 P00918 2/20 0.52
▸ CA9 Q16790 2/20 0.52
▸ CA1 P00915 1/20 0.52
▸ CYP2A6 P11509 2/20 0.50
▸ MAOB P27338 1/20 0.50
▸ ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8852392 1.00 PARP15 (0.63) PARP15PARP10PARP2KDM4ELMNA
SCHEMBL29582194 0.92 PARP15 (0.57) PARP15PARP10PARP2KDM4ELMNA
SCHEMBL378478 0.90 CYP19A1 (0.63) PARP15PARP10PARP2KDM4ELMNA
SCHEMBL921496 0.88 MAOA (0.56) PARP15PARP10PARP2KDM4ELMNA
SCHEMBL920674 0.88 MAOB (0.57) PARP15PARP10PARP2KDM4ELMNA
SCHEMBL4315032 0.88 CA12 (0.73) PARP15PARP10PARP2KDM4ELMNA
SCHEMBL459019 0.88 ALDH1A1 (0.73) PARP15PARP10PARP2KDM4ELMNA
SCHEMBL4314530 0.88 PARP15 (0.53) PARP15PARP10PARP2KDM4ELMNA
SCHEMBL2259191 0.88 MAOB (0.57) PARP15PARP10PARP2KDM4ELMNA
SCHEMBL7077780 0.88 PARP15 (0.53) PARP15PARP10PARP2KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111018706-B Synthesis method of 4, 4' -diphenyl ether dicarboxylic acid 大连天源基化学有限公司 2022-06-24 — — CN claimed
CN-111018706-A Synthesis method of 4, 4' -diphenyl ether dicarboxylic acid 大连天源基化学有限公司 2020-04-17 — — CN claimed
CN-104710387-A Disulfonamide macrocyclic compound and synthesis method thereof UNIV SOUTH CHINA NORMAL 2015-06-17 — — CN claimed
US-4389516-A POLYFUNCTIONAL MALEIMIDE OR CYANATE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1983-06-21 — — US claimed
JP-6279389-A — — None — — JP disclosed
CN-120092029-A Resin composition, cured product, prepreg, metal foil-clad laminate, resin composite sheet, and printed wiring board 三菱瓦斯化学株式会社 2025-06-03 — — CN disclosed
CN-119894957-A Epoxy resin composition, resin paste, film-type adhesive, printed circuit board, semiconductor chip package, and electronic device 旭化成株式会社 2025-04-25 — — CN disclosed
CN-119019680-A Covalent triazine skeleton adsorption separation membrane, preparation method thereof and method for separating and purifying acetonitrile-oxazole 广东工业大学 2024-11-26 — — CN disclosed
CN-116438244-B Crosslinkable organosiloxanes alkane modified reaction resins 瓦克化学股份公司 2024-08-30 — — CN disclosed
CN-114845874-B Resin sheet and printed circuit board 三菱瓦斯化学株式会社 2024-08-23 — — CN disclosed
CN-114787120-B Compound and method for producing same, resin composition, resin sheet, multilayer printed wiring board, and semiconductor device 三菱瓦斯化学株式会社 2024-08-09 — — CN disclosed
CN-114196204-B Prepreg, laminate, metal foil-clad laminate, printed wiring board, and multilayer printed wiring board 三菱瓦斯化学株式会社 2024-07-16 — — CN disclosed
US-5117002-A PREPARATION OF DIPHENYL ETHER OCCIDENTAL CHEMICAL CORPORATION (US) 1992-05-26 — — US disclosed
US-5084463-A Cardiovascular disorders AMERICAN HOME PRODUCTS CORPORATION (US) 1992-01-28 — — US disclosed
US-5084085-A Plant growth regulators FMC CORPORATION (US) 1992-01-28 — — US disclosed
EP-0193358-B1 METHOD OF PREPARING 3,3'-DINITRODIPHENYL ETHER MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-30 — — EP disclosed
EP-0193358-A1 Method of preparing 3,3'-dinitrodiphenyl ether MITSUI TOATSU CHEMICALS, Inc. (JP) 1986-09-03 — — EP disclosed
EP-0009163-B1 Substituted bisbenzimidazole derivatives, their preparation and antiprotozoic and antiviral agents HOECHST AKTIENGESELLSCHAFT (DE) 1982-06-30 — — EP disclosed
EP-0009163-A2 Substituted bisbenzimidazole derivatives, their preparation and antiprotozoic and antiviral agents HOECHST AKTIENGESELLSCHAFT (DE) 1980-04-02 — — EP disclosed
US-4156778-A Substituted bis-benzimidazolyl compounds; preparation and use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1979-05-29 — — US disclosed
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