Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 7/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 7/20 | 0.52 |
| ▸ | AR | P10275 | 12/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13989449 | 0.88 | AR (0.44) | CACNA1BAPBA1ARALDH1A1TP53 | |
| SCHEMBL13889764 | 0.87 | AR (0.54) | CACNA1BAPBA1AR | |
| SCHEMBL13989418 | 0.87 | AR (0.53) | CACNA1BAPBA1AR | |
| SCHEMBL13889352 | 0.86 | CACNA1B (0.43) | CACNA1BAPBA1ARALDH1A1TP53 | |
| SCHEMBL13482705 | 0.82 | AR (0.49) | AR | |
| SCHEMBL13989444 | 0.82 | AR (0.44) | AR | |
| SCHEMBL13889502 | 0.82 | AR (0.60) | CACNA1BAPBA1AR | |
| SCHEMBL13889850 | 0.82 | AR (0.74) | CACNA1BAPBA1AR | |
| SCHEMBL13889600 | 0.81 | CACNA1B (0.46) | CACNA1BAPBA1ARALDH1A1TP53 | |
| SCHEMBL13482341 | 0.81 | AR (0.65) | CACNA1BAPBA1ARALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517904-B2 | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-04-14 | — | — | US | disclosed |
| US-7470797-B2 | Fused heterocyclic imido and amido compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-30 | — | — | US | disclosed |