Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 7/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13889592 | 0.88 | CACNA1B (0.52) | ARCACNA1BAPBA1ALDH1A1TP53 | |
| SCHEMBL13481656 | 0.85 | AR (0.58) | AR | |
| SCHEMBL13889352 | 0.85 | CACNA1B (0.43) | ARCACNA1BAPBA1ALDH1A1TP53 | |
| SCHEMBL13889600 | 0.80 | CACNA1B (0.46) | ARCACNA1BAPBA1ALDH1A1TP53 | |
| SCHEMBL13989418 | 0.78 | AR (0.53) | ARCACNA1BAPBA1 | |
| SCHEMBL13889764 | 0.78 | AR (0.54) | ARCACNA1BAPBA1 | |
| SCHEMBL13989372 | 0.76 | ALDH1A1 (0.37) | ARCACNA1BAPBA1ALDH1A1TP53 | |
| SCHEMBL13889850 | 0.75 | AR (0.74) | ARCACNA1BAPBA1 | |
| SCHEMBL13482705 | 0.74 | AR (0.49) | AR | |
| SCHEMBL13989444 | 0.74 | AR (0.44) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470797-B2 | Fused heterocyclic imido and amido compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-30 | — | — | US | disclosed |