Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 17/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13889654 | 0.88 | AR (0.45) | ARCACNA1BAPBA1 | |
| SCHEMBL3182916 | 0.87 | AR (0.60) | AR | |
| SCHEMBL13480979 | 0.87 | AR (0.60) | AR | |
| SCHEMBL6369428 | 0.87 | AR (0.60) | AR | |
| SCHEMBL13482340 | 0.87 | AR (0.60) | AR | |
| SCHEMBL13889353 | 0.80 | CACNA1B (0.45) | ARCACNA1BAPBA1 | |
| SCHEMBL3187440 | 0.79 | AR (0.59) | AR | |
| SCHEMBL3173608 | 0.79 | AR (0.59) | AR | |
| SCHEMBL5942405 | 0.79 | AR (0.59) | AR | |
| SCHEMBL13989430 | 0.78 | AR (0.37) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517904-B2 | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-04-14 | — | — | US | disclosed |
| US-7470797-B2 | Fused heterocyclic imido and amido compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-30 | — | — | US | disclosed |