Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 6/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 6/20 | 0.45 |
| ▸ | AR | P10275 | 11/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13889352 | 0.87 | CACNA1B (0.43) | CACNA1BAPBA1ARALDH1A1TP53 | |
| SCHEMBL13480984 | 0.87 | AR (0.55) | AR | |
| SCHEMBL13482475 | 0.87 | AR (0.55) | AR | |
| SCHEMBL13889743 | 0.81 | AR (0.41) | CACNA1BAPBA1ARMEN1ALDH1A1 | |
| SCHEMBL13889653 | 0.80 | AR (0.44) | CACNA1BAPBA1AR | |
| SCHEMBL13482175 | 0.73 | CACNA1B (0.43) | CACNA1BAPBA1ARMEN1ALDH1A1 | |
| SCHEMBL13989449 | 0.71 | AR (0.44) | CACNA1BAPBA1ARMEN1ALDH1A1 | |
| SCHEMBL13807462 | 0.71 | AR (0.53) | CACNA1BAPBA1AR | |
| SCHEMBL13482341 | 0.71 | AR (0.65) | CACNA1BAPBA1ARMEN1ALDH1A1 | |
| SCHEMBL3173897 | 0.71 | AR (0.65) | CACNA1BAPBA1ARMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517904-B2 | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-04-14 | — | — | US | disclosed |