SCHEMBL13889702

SCHEMBL13889702

CN1c2ccccc2C(C)(C)C12C=Cc1c(ccc3cc(S(=O)(=O)O)ccc13)O2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.53
LMNA P02545 8/20 0.53
GAA P10253 5/20 0.53
MEN1 O00255 5/20 0.53
KMT2A Q03164 5/20 0.53
TDP1 Q9NUW8 4/20 0.53
NPSR1 Q6W5P4 3/20 0.53
RECQL P46063 3/20 0.53
HSD17B10 Q99714 3/20 0.53
ALPG P10696 1/20 0.53
TP53 P04637 1/20 0.53
ALOX15 P16050 1/20 0.53
SMN1; SMN2 Q16637 8/20 0.45
KDM4E B2RXH2 6/20 0.45
THRB P10828 5/20 0.45
L3MBTL1 Q9Y468 3/20 0.45
ALOX12 P18054 2/20 0.45
PKM P14618 2/20 0.45
ALDH1A1 P00352 6/20 0.42
HTT P42858 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16315814 0.84 MAPT (0.55) MAPTLMNAGAAMEN1KMT2A
SCHEMBL13889698 0.84 MAPT (0.71) MAPTLMNAGAAMEN1KMT2A
SCHEMBL8680040 0.83 MAPT (0.54) MAPTLMNAGAAMEN1KMT2A
SCHEMBL29931020 0.82 MAPT (0.63) MAPTLMNAGAAMEN1KMT2A
SCHEMBL29848328 0.82 MAPT (0.63) MAPTLMNAGAAMEN1KMT2A
SCHEMBL8685142 0.80 MAPT (0.71) MAPTLMNAGAAMEN1KMT2A
SCHEMBL8680360 0.79 MAPT (0.59) MAPTLMNAGAAMEN1KMT2A
SCHEMBL14077771 0.78 MAPT (0.49) MAPTLMNAGAAMEN1KMT2A
SCHEMBL8680016 0.75 MAPT (0.50) MAPTLMNAGAAMEN1KMT2A
SCHEMBL8862508 0.74 MAPT (0.44) MAPTLMNAGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7524605-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2009-04-28 US disclosed
US-20070082291-A1 Lithographic Printing Plate Precursor and Lithographic Printing Method FUJI PHOTO FILM CO., LTD. (JP) 2007-04-12 US disclosed