SCHEMBL14077771

SCHEMBL14077771

CCCCc1ccc2c3c(ccc2c1)OC1(C=C3)N(C)c2ccccc2C1(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.49
GAA P10253 4/20 0.49
LMNA P02545 4/20 0.49
NPSR1 Q6W5P4 3/20 0.49
RECQL P46063 3/20 0.49
TDP1 Q9NUW8 3/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
ALPG P10696 1/20 0.49
TP53 P04637 1/20 0.49
ALOX15 P16050 1/20 0.49
HSD17B10 Q99714 1/20 0.49
SMN1; SMN2 Q16637 5/20 0.44
THRB P10828 5/20 0.44
KDM4E B2RXH2 4/20 0.44
ALOX12 P18054 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
PKM P14618 2/20 0.44
HTT P42858 3/20 0.42
ALDH1A1 P00352 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16315814 0.83 MAPT (0.55) MAPTGAALMNANPSR1RECQL
SCHEMBL8680040 0.82 MAPT (0.54) MAPTGAALMNANPSR1RECQL
SCHEMBL1894170 0.81 MAPT (0.63) MAPTGAALMNANPSR1RECQL
SCHEMBL29931020 0.81 MAPT (0.63) MAPTGAALMNANPSR1RECQL
SCHEMBL29848328 0.81 MAPT (0.63) MAPTGAALMNANPSR1RECQL
SCHEMBL8863248 0.81 MAPT (0.57) MAPTGAALMNANPSR1RECQL
SCHEMBL8681962 0.80 MAPT (0.52) MAPTGAALMNANPSR1RECQL
SCHEMBL8680360 0.79 MAPT (0.59) MAPTGAALMNANPSR1RECQL
SCHEMBL13889702 0.78 MAPT (0.53) MAPTGAALMNANPSR1RECQL
SCHEMBL8680026 0.78 MAPT (0.45) MAPTGAALMNANPSR1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7425406-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2008-09-16 US disclosed
US-7425406-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2008-09-16 US disclosed