Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455871 | 0.82 | F10 (0.65) | F10PTGS2 | |
| SCHEMBL13677854 | 0.82 | F10 (0.82) | F10PTGS2 | |
| SCHEMBL8268508 | 0.82 | F10 (0.82) | F10PTGS2 | |
| SCHEMBL28956907 | 0.82 | PTGS2 (0.67) | F10PTGS2 | |
| SCHEMBL4448086 | 0.81 | F10 (0.64) | F10PTGS2 | |
| SCHEMBL13677849 | 0.81 | F10 (0.81) | F10PTGS2 | |
| SCHEMBL19647445 | 0.81 | F10 (0.62) | F10PTGS2 | |
| SCHEMBL13890614 | 0.81 | F10 (0.79) | F10PTGS2 | |
| SCHEMBL77342 | 0.81 | F10 (0.66) | F10PTGS2 | |
| SCHEMBL85613 | 0.81 | F10 (0.66) | F10PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720844-B1 | PYRROLIDINO-1,2-DICARBOXY-1-(PHENYLAMIDE)-2-(4-(3-OXO-MORPHOLINO-4-YL)-PHENYLAMIDE) DERIVATIVES AND RELATED COMPOUNDS FOR USE AS INHIBITORS OF COAGULATION FACTOR XA IN THE TREATMENT OF THROMBO-EMBOLIC DISEASES | MERCK PATENT GMBH (DE) | 2009-04-29 | — | — | EP | disclosed |