Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR3 | P25089 | 1/20 | 0.30 |
| ▸ | TSPO | P30536 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1637789 | 0.90 | CHRM3 (0.34) | FPR3TSPOCRHR1TMEM97 | |
| SCHEMBL1636123 | 0.86 | CHRM3 (0.31) | — | |
| SCHEMBL1638401 | 0.85 | KDM4E (0.32) | FPR3TSPOCRHR1TMEM97 | |
| SCHEMBL1637158 | 0.84 | CRHR1 (0.33) | FPR3TSPOCRHR1TMEM97 | |
| SCHEMBL1637882 | 0.82 | CRHR1 (0.33) | FPR3TSPOCRHR1TMEM97 | |
| SCHEMBL1638186 | 0.82 | CRHR1 (0.39) | FPR3TSPOCRHR1TMEM97 | |
| SCHEMBL1636914 | 0.78 | CRHR1 (0.35) | FPR3TSPOCRHR1TMEM97 | |
| SCHEMBL1637913 | 0.78 | CRHR1 (0.33) | FPR3TSPOCRHR1TMEM97 | |
| SCHEMBL13890557 | 0.77 | KDM4E (0.31) | — | |
| SCHEMBL1636786 | 0.77 | JAK2 (0.33) | FPR3TSPOCRHR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1787992-B1 | Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino group | TAISHO PHARMACEUTICAL CO LTD (JP) | 2009-04-29 | — | — | EP | disclosed |