Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13891090 | 1.00 | CSF1R (0.44) | CSF1RKIT | |
| SCHEMBL31263290 | 0.94 | CSF1R (0.44) | CSF1RKIT | |
| SCHEMBL13877974 | 0.94 | CSF1R (0.44) | CSF1RKIT | |
| SCHEMBL13877969 | 0.94 | CSF1R (0.44) | CSF1RKIT | |
| SCHEMBL13877960 | 0.91 | CSF1R (0.41) | CSF1RKIT | |
| SCHEMBL4231432 | 0.91 | CSF1R (0.41) | CSF1RKIT | |
| SCHEMBL13877963 | 0.91 | CSF1R (0.41) | CSF1RKIT | |
| SCHEMBL4231785 | 0.90 | CSF1R (0.45) | CSF1RKIT | |
| SCHEMBL4234108 | 0.89 | CSF1R (0.44) | CSF1RKIT | |
| SCHEMBL13878008 | 0.89 | CSF1R (0.44) | CSF1RKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105296-A1 | INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105296-A1 | INHIBITORS OF C-FMS KINASE | MUSK, FRK, FES | CSF1R 59/4885KIT 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.