Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 8/20 | 0.43 |
| ▸ | BRAF | P15056 | 8/20 | 0.43 |
| ▸ | TACR1 | P25103 | 8/20 | 0.42 |
| ▸ | CETP | P11597 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14514048 | 0.69 | TACR1 (0.44) | TACR1 | |
| SCHEMBL7522146 | 0.69 | TACR1 (0.60) | TACR1 | |
| SCHEMBL4262145 | 0.68 | TACR1 (0.48) | RAF1BRAFTACR1 | |
| SCHEMBL5781484 | 0.67 | TACR1 (0.68) | RAF1BRAFTACR1 | |
| SCHEMBL5528489 | 0.66 | GPBAR1 (0.42) | TACR1 | |
| SCHEMBL6988382 | 0.66 | TACR1 (0.48) | TACR1 | |
| SCHEMBL6992641 | 0.65 | TACR1 (0.45) | TACR1 | |
| SCHEMBL6990714 | 0.64 | TACR1 (0.57) | TACR1 | |
| SCHEMBL6988418 | 0.63 | GPBAR1 (0.47) | TACR1 | |
| SCHEMBL6993514 | 0.62 | TACR1 (0.62) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1473295-B1 | FUSED BICYCLIC PYRIMIDINE DERIVATIVES | KYORIN SEIYAKU KK (JP) | 2009-04-01 | — | — | EP | disclosed |