Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 11/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 9/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5528489 | 0.78 | GPBAR1 (0.42) | TACR1GPBAR1 | |
| SCHEMBL6990714 | 0.74 | TACR1 (0.57) | TACR1GPBAR1 | |
| SCHEMBL6988382 | 0.73 | TACR1 (0.48) | TACR1GPBAR1 | |
| SCHEMBL7522146 | 0.72 | TACR1 (0.60) | TACR1GPBAR1 | |
| SCHEMBL14434370 | 0.71 | TACR1 (0.37) | TACR1GPBAR1 | |
| SCHEMBL6992641 | 0.70 | TACR1 (0.45) | TACR1GPBAR1 | |
| SCHEMBL6988418 | 0.70 | GPBAR1 (0.47) | TACR1GPBAR1 | |
| SCHEMBL6986187 | 0.70 | TACR1 (0.52) | TACR1GPBAR1 | |
| SCHEMBL13891736 | 0.69 | RAF1 (0.43) | TACR1 | |
| SCHEMBL6990538 | 0.67 | TACR1 (0.59) | TACR1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1489083-B1 | FUSED BICYCLIC PYRIDINE DERIVATIVE AS TACHYKININ RECEPTOR ANTAGONIST | KYORIN SEIYAKU KK (JP) | 2007-06-06 | — | — | EP | disclosed |