Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNG2 | P59768 | 10/20 | 0.57 |
| ▸ | GNB1 | P62873 | 10/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.57 |
| ▸ | HSPA1A | P0DMV8 | 4/20 | 0.57 |
| ▸ | HSPA8 | P11142 | 4/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | GRK2 | P25098 | 1/20 | 0.57 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.57 |
| ▸ | BRCA1 | P38398 | 3/20 | 0.50 |
| ▸ | GAPDH | P04406 | 1/20 | 0.49 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16556417 | 0.92 | GNG2 (0.65) | GNG2GNB1HPGDALOX15HSD17B10 | |
| SCHEMBL13891750 | 0.87 | GNG2 (0.66) | GNG2GNB1HPGDALOX15HSD17B10 | |
| SCHEMBL13891751 | 0.87 | GNG2 (0.69) | GNG2GNB1HPGDALOX15HSD17B10 | |
| SCHEMBL13891752 | 0.85 | GNG2 (0.68) | GNG2GNB1HPGDALOX15HSD17B10 | |
| SCHEMBL13320772 | 0.85 | GNG2 (0.68) | GNG2GNB1HPGDALOX15HSD17B10 | |
| SCHEMBL13352371 | 0.85 | GNG2 (0.68) | GNG2GNB1HPGDALOX15HSD17B10 | |
| SCHEMBL2779115 | 0.84 | GNG2 (0.66) | GNG2GNB1HPGDALOX15HSD17B10 | |
| SCHEMBL13891722 | 0.81 | GNG2 (0.71) | GNG2GNB1HPGDALOX15HSD17B10 | |
| SCHEMBL13891724 | 0.81 | GNG2 (0.71) | GNG2GNB1HPGDALOX15HSD17B10 | |
| SCHEMBL13891728 | 0.81 | GNG2 (0.71) | GNG2GNB1HPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020677-A9 | COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING | UNIV ROCHESTER (US) | 2009-04-16 | — | — | WO | disclosed |
| WO-2009020677-A2 | COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING | UNIVERSITY OF ROCHESTER (US) | 2009-02-12 | — | — | WO | disclosed |