Sugi Predict

Sugi Predict / Targets / GNG2

GNG2

Guanine nucleotide-binding protein G(I)/G(S)/ · P59768 · GNG2 on Sugi Atlas →

5,768 patent compounds predicted against GNG2, 3,926 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL2777685 SCHEMBL2777685 1.00 11/20
SCHEMBL2778459 SCHEMBL2778459 1.00 10/20
SCHEMBL2790401 SCHEMBL2790401 1.00 10/20
SCHEMBL2789188 SCHEMBL2789188 0.82 10/20
SCHEMBL2779461 SCHEMBL2779461 0.67 10/20
SCHEMBL2779115 SCHEMBL2779115 0.66 10/20
SCHEMBL2789905 SCHEMBL2789905 0.65 10/20
SCHEMBL2779337 SCHEMBL2779337 1.00 9/20
SCHEMBL2846323 SCHEMBL2846323 1.00 9/20
SCHEMBL2846330 SCHEMBL2846330 1.00 9/20
SCHEMBL2848097 SCHEMBL2848097 0.80 9/20
SCHEMBL2782525 SCHEMBL2782525 0.70 9/20
SCHEMBL2777698 SCHEMBL2777698 0.69 9/20
SCHEMBL2848109 SCHEMBL2848109 0.65 9/20
SCHEMBL2840949 SCHEMBL2840949 0.64 8/20
SCHEMBL2777300 SCHEMBL2777300 1.00 7/20
Pyrogallol Red Pyrogallol Red (SCHEMBL3398009) 0.66 7/20
SCHEMBL2778161 SCHEMBL2778161 1.00 5/20
SCHEMBL2778373 SCHEMBL2778373 1.00 5/20
SCHEMBL2779595 SCHEMBL2779595 1.00 5/20

Clinical trials — most relevant to GNG2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Treatment With HMG-COA Reductase Inhibitor of Growth and Bone Abnormalities in Children With Noonan Syndrome PHASE3COMPLETED
PET Imaging of Phosphodiesterase-4 (PDE4) in Brain and Peripheral Organs of McCune-Albright Syndrome PHASE1/PHASE2COMPLETED
ADH1 and ADH2 Disease Monitoring Study (DMS) nanACTIVE_NOT_RECRUITING
Histamine Responsiveness in McCune-Albright Syndrome nanCOMPLETED
Sexually Dimorphic Effects of GHRH in Adult Growth Hormone Testing nanCOMPLETED
Adrenocorticotropic Hormone (ACTH) Stimulation and G Protein nanCOMPLETED
Genetic Analysis of Gray Platelet Syndrome nanCOMPLETED
GNE-Myopathy Disease Monitoring Program (GNEM-DMP): A Registry and Prospective Observational Natural History Study to Assess GNE Myopathy or Hereditary Inclusion Body Myopathy (HIBM) nanCOMPLETED
Biomarker for Sanfilippo Type A-B-C-D Disease (BioSanfilippo) nanWITHDRAWN
Study on the Carcinogenesis of Gα12 in Oral Cancer, and the Treatment of Oral Cancer Using Ga12 Inhibitor. nanUNKNOWN
Long-read Genome Sequencing for the Molecular Diagnosis of Dystonia nanRECRUITING
Anesthetic Methods and Gene Expression Profile nanCOMPLETED
GNAO1 Natural History Study nanUNKNOWN
Genetic Investigations in Children With Developmental and Epileptic Encephalopathies in Ho Chi Minh City, Vietnam nanUNKNOWN
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma nanRECRUITING
Non Motor Symptoms in Glucocerebrosidase-related Parkinson's Disease nanENROLLING_BY_INVITATION
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
A Natural History Study of Patients With GNE Myopathy and GNE-Related Diseases nanCOMPLETED
Quality of Life, Fatigue and Cognitive, Affective and Emotional Dysfunction in Patients With Cushing's Syndrome nanACTIVE_NOT_RECRUITING
Symptom Clusters and Immune Markers in Patients With Chronic Obstructive Pulmonary Disease (COPD) - a Longitudinal Study nanCOMPLETED
The Genetic Study of Primary Angle-Closure Glaucoma nanUNKNOWN
Study of the Genetic and Epigenetic Causes of Recurrent Hydatidiform Moles nanACTIVE_NOT_RECRUITING
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients nanRECRUITING
Evaluation of rhGH Replacement Therapy in Patients With Pseudohypoparathyroidism Type Ia (PHP Ia) nanUNKNOWN
Characterization of WAGR Syndrome and Other Chromosome 11 Gene Deletions nanCOMPLETED
Use of miRNAs in Growth Hormone Deficiency (GHD) nanUNKNOWN
Incidental Genomics nanACTIVE_NOT_RECRUITING
Prospective Evaluation and Molecular Profiling in People With Gastric Tumors nanCOMPLETED
Clinical and Laboratory Analysis of Familial Cancer nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a GNG2 binder may also engage these)

ProteinNameSimilarity
P63213 — 1.000 P63213 →
P63212 — 1.000 P63212 →
P63077 — 1.000 P63077 →
Q5R639 — 1.000 Q5R639 →
Q9UK08 — 1.000 Q9UK08 →
Q9CXP8 — 1.000 Q9CXP8 →
P50150 — 1.000 P50150 →
Q61016 — 1.000 Q61016 →
P63078 — 1.000 P63078 →
Q5R7U4 — 1.000 Q5R7U4 →
O60262 — 1.000 O60262 →
P63216 — 0.999 P63216 →
P63215 — 0.999 P63215 →
Q5RBQ0 — 0.998 Q5RBQ0 →
P54406 — 0.998 P54406 →
P43425 — 0.998 P43425 →
P63219 — 0.998 P63219 →
Q80SZ7 — 0.998 Q80SZ7 →
P50153 — 0.997 P50153 →
Q4VT26 — 0.997 Q4VT26 →
Q61017 — 0.997 Q61017 →
P63218 — 0.996 P63218 →
A0A804HLA8 — 0.995 A0A804HLA8 →
P50154 — 0.995 P50154 →
Q9P2W3 — 0.995 Q9P2W3 →
P50151 — 0.995 P50151 →
P63214 — 0.994 P63214 →
P38040 — 0.993 P38040 →
P61952 — 0.993 P61952 →
Q6CPB4 — 0.993 Q6CPB4 →