Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15458042 | 0.93 | CYP2C19 (0.42) | TSHRNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL15458038 | 0.93 | CYP2C19 (0.42) | TSHRNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL10203337 | 0.93 | TSHR (0.39) | TSHRNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL15458034 | 0.93 | CYP2C19 (0.42) | TSHRNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL15458105 | 0.91 | MAPT (0.57) | TSHRNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL2230579 | 0.89 | TSHR (0.55) | TSHRNPC1RAB9AMAPTMAPK1 | |
| SCHEMBL17973760 | 0.88 | ACHE (0.48) | NPC1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL16773971 | 0.88 | CYP2C19 (0.39) | TSHRNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL17973770 | 0.85 | NPC1 (0.34) | TSHRNPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL13460330 | 0.85 | CYP2C9 (0.35) | TSHRNPC1RAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2048176-A1 | POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE | Sumitomo Chemical Company, Limited (JP) | 2009-04-15 | — | — | EP | disclosed |
| US-20080103273-A1 | Polytriazoles constructed by 1, 3-dipolar cycloaddition | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2008-05-01 | — | — | US | disclosed |