Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15892789 | 0.89 | TDP1 (0.59) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL15298820 | 0.89 | TDP1 (0.43) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL15892785 | 0.82 | TDP1 (0.52) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL13295366 | 0.81 | TDP1 (0.79) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL7153751 | 0.81 | TDP1 (0.79) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL7154920 | 0.81 | TDP1 (0.79) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL7149904 | 0.81 | TDP1 (0.79) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL4530510 | 0.80 | TDP1 (0.50) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL23720379 | 0.79 | TDP1 (0.82) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL15895102 | 0.78 | TDP1 (0.48) | TDP1TSHRTRPV1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018033719-A1 | COMPOUNDS | UNIVERSITETET I OSLO (NO) | 2018-02-22 | — | — | WO | disclosed |