Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15496479 | 0.92 | TDP1 (0.57) | TDP1TSHRTRPV1ALOX15CHRM2 | |
| SCHEMBL14747313 | 0.89 | TDP1 (0.54) | TDP1TSHRTRPV1ALOX15CHRM2 | |
| SCHEMBL15892789 | 0.89 | TDP1 (0.59) | TDP1TSHRTRPV1ALOX15CHRM2 | |
| SCHEMBL15892785 | 0.82 | TDP1 (0.52) | TDP1TSHRTRPV1ALOX15CHRM2 | |
| SCHEMBL11288893 | 0.80 | TDP1 (0.46) | TDP1TSHRTRPV1ALOX15CHRM2 | |
| SCHEMBL13893506 | 0.80 | TDP1 (0.50) | TDP1TSHRTRPV1ALOX15CHRM2 | |
| SCHEMBL1566731 | 0.79 | TDP1 (0.46) | TDP1TSHRTRPV1ALOX15 | |
| SCHEMBL1941509 | 0.79 | TDP1 (0.46) | TDP1TSHRTRPV1ALOX15 | |
| SCHEMBL16312958 | 0.78 | TDP1 (0.81) | TDP1TSHRTRPV1ALOX15ABCB1 | |
| SCHEMBL16627355 | 0.78 | TDP1 (0.75) | TDP1TSHRTRPV1ALOX15ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140295403-A1 | DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2014-10-02 | — | — | US | disclosed |
| US-8632966-B2 | Detection of biological molecules by differential partitioning of enzyme substrates and products | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2014-01-21 | — | — | US | disclosed |
| US-20130217041-A1 | DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2013-08-22 | — | — | US | disclosed |
| US-8377686-B2 | Detection of biological molecules by differential partitioning of enzyme substrates and products | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2013-02-19 | — | — | US | disclosed |
| US-20090117600-A1 | Detection of biological molecules by differential partitioning of enzyme substrates and products | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2009-05-07 | — | — | US | disclosed |
| US-7402426-B2 | Analyzing microorganism associated with an enzyme in a sample water, food, soil, or a biological sample, enzyme-linked immunosorbent assay, automatic detect fluorescence with optical fiber, separate with polydimethylsiloxane films; diagnostic kits | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2008-07-22 | — | — | US | disclosed |
| EP-1539986-B1 | DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS | UNIV KINGSTON (CA) | 2007-07-18 | — | — | EP | disclosed |
| EP-1539986-A1 | DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS | Queen's University at Kingston (CA) | 2005-06-15 | — | — | EP | disclosed |
| US-20040106164-A1 | Analyzing microorganism associated with an enzyme in a sample water, food, soil, or a biological sample, enzyme-linked immunosorbent assay, automatic detect fluorescence with optical fiber, separate with polydimethylsiloxane films; diagnostic kits | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2004-06-03 | — | — | US | disclosed |
| WO-2004027084-A1 | DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2004-04-01 | — | — | WO | disclosed |