Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13894047 | 0.89 | BTK (0.47) | BTK | |
| SCHEMBL13893948 | 0.87 | BTK (0.51) | BTK | |
| SCHEMBL13894042 | 0.85 | BTK (0.44) | BTK | |
| SCHEMBL1776878 | 0.85 | BTK (0.54) | BTK | |
| SCHEMBL13894044 | 0.85 | BTK (0.51) | BTK | |
| SCHEMBL13893944 | 0.83 | BTK (0.53) | BTK | |
| SCHEMBL13893941 | 0.83 | BTK (0.55) | BTK | |
| SCHEMBL13894053 | 0.80 | BTK (0.45) | BTK | |
| SCHEMBL13893894 | 0.77 | BTK (0.45) | BTKMAPT | |
| SCHEMBL13893893 | 0.77 | BTK (0.48) | BTKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053269-A1 | NOVEL KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-04-30 | — | — | WO | disclosed |