Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 6/20 | 0.59 |
| ▸ | ICAM1 | P05362 | 6/20 | 0.59 |
| ▸ | ITGAL | P20701 | 6/20 | 0.59 |
| ▸ | PRLHR | P49683 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13894076 | 0.86 | ITGB2 (0.72) | ITGB2ICAM1ITGAL | |
| SCHEMBL12063267 | 0.78 | ITGB2 (0.74) | ITGB2ICAM1ITGAL | |
| SCHEMBL12169934 | 0.73 | ITGB2 (0.68) | ITGB2ICAM1ITGAL | |
| SCHEMBL25912265 | 0.73 | ITGB2 (0.67) | ITGB2ICAM1ITGAL | |
| SCHEMBL18868507 | 0.73 | ITGB2 (0.54) | ITGB2ICAM1ITGALPRLHRALDH1A1 | |
| SCHEMBL16851828 | 0.72 | ITGB2 (0.76) | ITGB2ICAM1ITGAL | |
| SCHEMBL12054458 | 0.72 | ITGB2 (0.76) | ITGB2ICAM1ITGAL | |
| SCHEMBL13894282 | 0.72 | ITGB2 (0.65) | ITGB2ICAM1ITGAL | |
| SCHEMBL25912167 | 0.72 | ITGB2 (0.65) | ITGB2ICAM1ITGAL | |
| SCHEMBL12188988 | 0.71 | ITGB2 (0.64) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009054914-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC RETINOPATHY | SARCODE CORPORATION (US) | 2009-04-30 | — | — | WO | disclosed |