Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 19/20 | 0.72 |
| ▸ | ICAM1 | P05362 | 19/20 | 0.72 |
| ▸ | ITGAL | P20701 | 19/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12063267 | 0.88 | ITGB2 (0.74) | ITGB2ICAM1ITGAL | |
| SCHEMBL13894057 | 0.86 | ITGB2 (0.59) | ITGB2ICAM1ITGAL | |
| SCHEMBL12169934 | 0.84 | ITGB2 (0.68) | ITGB2ICAM1ITGAL | |
| SCHEMBL25912265 | 0.83 | ITGB2 (0.67) | ITGB2ICAM1ITGAL | |
| SCHEMBL13894120 | 0.83 | ITGB2 (0.55) | ITGB2ICAM1ITGAL | |
| SCHEMBL12054458 | 0.82 | ITGB2 (0.76) | ITGB2ICAM1ITGAL | |
| SCHEMBL16851828 | 0.82 | ITGB2 (0.76) | ITGB2ICAM1ITGAL | |
| SCHEMBL13894282 | 0.81 | ITGB2 (0.65) | ITGB2ICAM1ITGAL | |
| SCHEMBL25912167 | 0.81 | ITGB2 (0.65) | ITGB2ICAM1ITGAL | |
| SCHEMBL4756023 | 0.81 | ITGB2 (0.64) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3167886-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF MACULAR EDEMA | SARcode Bioscience Inc. (US) | 2017-05-17 | — | — | EP | disclosed |
| EP-2209371-B1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC RETINOPATHY | SARCODE BIOSCIENCE INC (US) | 2017-01-04 | — | — | EP | disclosed |
| WO-2009054914-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC RETINOPATHY | SARCODE CORPORATION (US) | 2009-04-30 | — | — | WO | disclosed |