Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 20/20 | 0.55 |
| ▸ | ICAM1 | P05362 | 20/20 | 0.55 |
| ▸ | ITGAL | P20701 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13813629 | 0.81 | ITGB2 (0.78) | ITGB2ICAM1ITGAL | |
| SCHEMBL23153574 | 0.76 | ITGB2 (0.69) | ITGB2ICAM1ITGAL | |
| SCHEMBL18868506 | 0.69 | ITGB2 (0.64) | ITGB2ICAM1ITGAL | |
| SCHEMBL18362364 | 0.69 | ITGB2 (0.71) | ITGB2ICAM1ITGAL | |
| SCHEMBL10129691 | 0.68 | ITGB2 (0.73) | ITGB2ICAM1ITGAL | |
| SCHEMBL13894130 | 0.68 | ITGB2 (0.62) | ITGB2ICAM1ITGAL | |
| SCHEMBL13894061 | 0.67 | ITGB2 (0.62) | ITGB2ICAM1ITGAL | |
| SCHEMBL12459907 | 0.67 | HPGDS (0.39) | — | |
| SCHEMBL879397 | 0.67 | ITGB2 (0.78) | ITGB2ICAM1ITGAL | |
| SCHEMBL10129831 | 0.67 | ITGB2 (0.81) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009054914-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC RETINOPATHY | SARCODE CORPORATION (US) | 2009-04-30 | — | — | WO | disclosed |