Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | ITGB2 | P05107 | 18/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 18/20 | 0.49 |
| ▸ | ITGAL | P20701 | 18/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13894108 | 0.81 | ITGB2 (0.65) | HDAC6ITGB2ICAM1ITGAL | |
| SCHEMBL13894281 | 0.80 | ITGB2 (0.56) | HDAC6ITGB2ICAM1ITGAL | |
| SCHEMBL13894068 | 0.80 | HDAC6 (0.45) | HDAC6ITGB2ICAM1ITGAL | |
| SCHEMBL13894069 | 0.80 | ITGB2 (0.67) | HDAC6ITGB2ICAM1ITGAL | |
| SCHEMBL13894233 | 0.77 | ITGB2 (0.49) | HDAC6ITGB2ICAM1ITGAL | |
| SCHEMBL13813645 | 0.77 | ITGB2 (0.74) | ITGB2ICAM1ITGAL | |
| SCHEMBL13821871 | 0.77 | ITGB2 (0.50) | HDAC6ITGB2ICAM1ITGAL | |
| SCHEMBL16351768 | 0.77 | ITGB2 (0.54) | ITGB2ICAM1ITGAL | |
| SCHEMBL19158066 | 0.77 | ITGB2 (0.73) | ITGB2ICAM1ITGAL | |
| SCHEMBL4756017 | 0.77 | ITGB2 (0.73) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009054914-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC RETINOPATHY | SARCODE CORPORATION (US) | 2009-04-30 | — | — | WO | disclosed |