Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 13/20 | 0.65 |
| ▸ | ICAM1 | P05362 | 13/20 | 0.65 |
| ▸ | ITGAL | P20701 | 13/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18867795 | 0.85 | ITGB2 (0.69) | ITGB2ICAM1ITGALHDAC6CYP2C9 | |
| SCHEMBL13665300 | 0.85 | ITGB2 (0.75) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL13894063 | 0.84 | ITGB2 (0.70) | ITGB2ICAM1ITGALHDAC6ALDH1A1 | |
| SCHEMBL18868483 | 0.84 | ITGB2 (0.74) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL18868611 | 0.82 | ITGB2 (0.65) | ITGB2ICAM1ITGALHDAC6CYP2C9 | |
| SCHEMBL13894118 | 0.81 | HDAC6 (0.51) | ITGB2ICAM1ITGALHDAC6 | |
| SCHEMBL13894281 | 0.80 | ITGB2 (0.56) | ITGB2ICAM1ITGALHDAC6 | |
| SCHEMBL25912527 | 0.80 | ITGB2 (0.73) | ITGB2ICAM1ITGAL | |
| SCHEMBL13658128 | 0.80 | ITGB2 (1.00) | ITGB2ICAM1ITGAL | |
| SCHEMBL13894069 | 0.80 | ITGB2 (0.67) | ITGB2ICAM1ITGALHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009054914-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC RETINOPATHY | SARCODE CORPORATION (US) | 2009-04-30 | — | — | WO | disclosed |