Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13094453 | 0.84 | CKS1B (0.55) | CNR2PIK3CAPTGESCKS1BSKP1 | |
| SCHEMBL3075253 | 0.81 | PTGES (0.62) | CNR2PIK3CAPTGESKMT2A | |
| SCHEMBL3264562 | 0.80 | GAA (0.59) | CNR2PIK3CACKS1BSKP1SKP2 | |
| SCHEMBL13279367 | 0.77 | PIK3CA (0.52) | CNR2PIK3CALMNAHTTSMN1; SMN2 | |
| SCHEMBL13094458 | 0.77 | CNR2 (0.50) | CNR2PIK3CAPTGESCKS1BSKP1 | |
| SCHEMBL25400235 | 0.76 | PIK3CA (0.51) | CNR2PIK3CAPTGESLMNAHTT | |
| SCHEMBL3101638 | 0.76 | PTGES (0.56) | CNR2PIK3CAPTGES | |
| SCHEMBL27077768 | 0.76 | PIK3CA (0.51) | CNR2PIK3CALMNAHTTSMN1; SMN2 | |
| SCHEMBL4058660 | 0.76 | GAA (0.64) | PIK3CACKS1BSKP1SKP2LMNA | |
| SCHEMBL3078363 | 0.75 | PTGES (0.52) | CNR2PTGESCKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009055357-A1 | DIAZEPANE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-30 | — | — | WO | disclosed |