Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.33 |
| ▸ | CA9 | Q16790 | 6/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | HK1 | P19367 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9593444 | 0.75 | CYP3A4 (0.48) | CA12CA9CA2CA1NLRP3 | |
| SCHEMBL7743372 | 0.75 | CYP3A4 (0.48) | CA12CA9CA2CA1NLRP3 | |
| SCHEMBL15420995 | 0.75 | CYP3A4 (0.48) | CA12CA9CA2CA1NLRP3 | |
| SCHEMBL9564690 | 0.75 | CYP3A4 (0.48) | CA12CA9CA2CA1NLRP3 | |
| SCHEMBL1567471 | 0.75 | — | — | |
| SCHEMBL3927779 | 0.73 | TSHR (0.37) | NLRP3TSHR | |
| SCHEMBL1469868 | 0.73 | TSHR (0.37) | NLRP3TSHR | |
| SCHEMBL3921362 | 0.73 | TSHR (0.37) | NLRP3TSHR | |
| SCHEMBL3926832 | 0.73 | TSHR (0.37) | NLRP3TSHR | |
| SCHEMBL3921354 | 0.73 | TSHR (0.37) | NLRP3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517891-B2 | Camptothecin derivatives and improved synthetic methods | GLYCONIX CORPORATION (US) | 2009-04-14 | — | — | US | disclosed |