Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 9/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564690 | 1.00 | CYP3A4 (0.48) | CYP3A4MAPTALDH1A1CYP2C19TSHR | |
| SCHEMBL9593444 | 1.00 | CYP3A4 (0.48) | CYP3A4MAPTALDH1A1CYP2C19TSHR | |
| SCHEMBL7743372 | 1.00 | CYP3A4 (0.48) | CYP3A4MAPTALDH1A1CYP2C19TSHR | |
| SCHEMBL14568421 | 0.85 | CYP3A4 (0.46) | CYP3A4MAPTALDH1A1CYP2C19TSHR | |
| SCHEMBL6512353 | 0.77 | CYP3A4 (0.52) | CYP3A4MAPTALDH1A1CYP2C19TSHR | |
| SCHEMBL6512348 | 0.77 | CYP3A4 (0.52) | CYP3A4MAPTALDH1A1CYP2C19TSHR | |
| SCHEMBL25246184 | 0.75 | NLRP3 (0.61) | CYP3A4MAPTALDH1A1CYP2C19TSHR | |
| SCHEMBL13895495 | 0.75 | CA12 (0.33) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL13163828 | 0.73 | CYP3A4 (0.59) | CYP3A4MAPTALDH1A1CYP2C19TSHR | |
| SCHEMBL16379575 | 0.73 | CYP3A4 (0.49) | CYP3A4MAPTALDH1A1CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026075-A1 | POLYMERISATION PROCESSES | THE UNIVERSITY OF BATH (GB) | 2024-01-25 | — | — | US | disclosed |
| US-11191273-B2 | Methods of making pyranopyrans such as pyranopyran nitrile and methods of using pyranopyrans such as pyranopyran nitrile | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2021-12-07 | — | — | US | disclosed |
| US-20200093132-A1 | Methods Of Making Pyranopyrans Such As Pyranopyran Nitrile And Methods of Using Pyranopyrans Such As Pyranopyran Nitrile | VILLANOVA UNIVERSITY | 2020-03-26 | — | — | US | disclosed |
| EP-2694472-B1 | SULFONAMIDE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2020-03-11 | — | — | EP | disclosed |
| US-9527807-B2 | Sulfonamide derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-12-27 | — | — | US | disclosed |
| US-20140024650-A1 | SULFONAMIDE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200093132-A1 | Methods Of Making Pyranopyrans Such As Pyranopyran Nitrile And Methods of Using Pyranopyrans Such As Pyranopyran Nitrile | CBR1, NOX1, NOX3 | CYP3A4 92/4885MAPT 4150/4885ALDH1A1 419/4885 |
| US-20140024650-A1 | SULFONAMIDE DERIVATIVE AND USE THEREOF | GRIN2A, GRIN2B, SLC1A2 | CYP3A4 2222/4885MAPT 175/4885ALDH1A1 143/4885 |
| US-11191273-B2 | Methods of making pyranopyrans such as pyranopyran nitrile and methods of using pyranopyrans such as pyranopyran nitrile | CBR1, NOX1, NOX3 | CYP3A4 92/4885MAPT 4150/4885ALDH1A1 419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.