Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13896293 | 0.77 | MEN1 (0.48) | MEN1CYP3A4ALOX15KMT2APTPN1 | |
| SCHEMBL28120876 | 0.73 | MEN1 (0.52) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL12953253 | 0.72 | SMPD1 (0.39) | MEN1CYP3A4ALOX15KMT2ACDC25B | |
| SCHEMBL17269277 | 0.72 | MEN1 (0.60) | MEN1CYP3A4ALOX15KMT2APTPN1 | |
| SCHEMBL17269083 | 0.72 | MEN1 (0.60) | MEN1CYP3A4ALOX15KMT2APTPN1 | |
| SCHEMBL9709450 | 0.71 | MEN1 (0.48) | MEN1CYP3A4ALOX15KMT2APTPN1 | |
| SCHEMBL23244046 | 0.71 | MEN1 (0.46) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL28954181 | 0.71 | MEN1 (0.49) | MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL17239377 | 0.71 | ALOX15 (1.00) | MEN1CYP3A4ALOX15KMT2APTPN1 | |
| SCHEMBL8079400 | 0.71 | ALOX15 (1.00) | MEN1CYP3A4ALOX15KMT2APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8313885-B2 | Lithographic printing plate precursor comprising bi-functional compounds | AGFA GRAPHICS NV (BE) | 2012-11-20 | — | — | US | disclosed |
| US-20070105041-A1 | Lithographic printing plate comprising bi-functional compounds | AGFA-GEVAERT (BE) | 2007-05-10 | — | — | US | disclosed |