SCHEMBL13898262

SCHEMBL13898262

C=CCC(C(=O)c1ccco1)C(=O)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
AGTR1 P30556 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
GAA P10253 1/20 0.39
TSHR P16473 1/20 0.38
PTPN1 P18031 1/20 0.36
ALDH1A1 P00352 4/20 0.35
RECQL P46063 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
KDM4E B2RXH2 2/20 0.35
THRB P10828 1/20 0.35
APEX1 P27695 1/20 0.35
MAPT P10636 2/20 0.35
ERCC5 P28715 1/20 0.35
FEN1 P39748 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5386614 0.73 KMT2A (0.49) POLBMEN1KMT2AAGTR1SMN1; SMN2
SCHEMBL10457332 0.73 GRIK1 (0.32) POLBSMN1; SMN2ALDH1A1
SCHEMBL6135938 0.72 CYP2C19 (0.46) POLBMEN1KMT2ASMN1; SMN2CES2
SCHEMBL6435640 0.70 KDM4E (0.47) MEN1KMT2ASMN1; SMN2CES2CES1
SCHEMBL28197369 0.70 POLB (0.56) POLBMEN1KMT2AAGTR1SMN1; SMN2
SCHEMBL9823675 0.69 GRIK1 (0.38) MAPT
SCHEMBL28184355 0.67 KMT2A (0.58) POLBMEN1KMT2AAGTR1SMN1; SMN2
SCHEMBL10457174 0.67
SCHEMBL5209634 0.66 KMT2A (0.51) POLBMEN1KMT2AAGTR1SMN1; SMN2
SCHEMBL7073482 0.66 CES1 (0.58) POLBMEN1KMT2AAGTR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7504046-B2 Polymer grafted alkaline earth aluminate phosphor through coordination bond DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2009-03-17 US disclosed
US-7504046-B2 Polymer grafted alkaline earth aluminate phosphor through coordination bond DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2009-03-17 US disclosed
US-20070221886-A1 Polymer grafted alkali earth aluminate phosphor through coordination bond DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2007-09-27 US disclosed
US-20070221886-A1 Polymer grafted alkali earth aluminate phosphor through coordination bond DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2007-09-27 US disclosed