SCHEMBL9823675

SCHEMBL9823675

C=CCC(C(=O)O)C(=O)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.38
GRIK2 Q13002 2/20 0.38
CYP2C19 P33261 1/20 0.37
CPA1 P15085 1/20 0.37
ABCC4 O15439 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10457332 0.91 GRIK1 (0.32) GRIK1GRIK2CYP2C19CPA1
SCHEMBL9286610 0.86 GRIK1 (0.32) GRIK1GRIK2CYP2C19CPA1
SCHEMBL10457174 0.83
SCHEMBL31636 0.78 GRIK1 (0.48) GRIK1GRIK2CYP2C19CPA1ABCC4
SCHEMBL10574699 0.77 ALDH1A1 (0.38)
Ammonia Solution, Strong SCHEMBL6396419 0.76 GRIK1 (0.46) GRIK1GRIK2CYP2C19CPA1ABCC4
Potassium SCHEMBL31299609 0.76 GRIK1 (0.46) GRIK1GRIK2CYP2C19CPA1ABCC4
SCHEMBL31299617 0.76 GRIK1 (0.46) GRIK1GRIK2CYP2C19CPA1ABCC4
Lithium SCHEMBL31299623 0.76 GRIK1 (0.46) GRIK1GRIK2CYP2C19CPA1ABCC4
SCHEMBL31718026 0.74 GRIK1 (0.42) GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0265305-B1 5-PYRAZOLONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AS HERBICIDES AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1991-06-12 EP disclosed
US-4943673-A Novel metal-diketone absorbents for olefins AIR PRODUCTS AND CHEMICALS, INC. (US) 1990-07-24 US disclosed
US-4877425-A FROM HYDROCARBON FEEDSTREAMS, POLLUTION CONTROL AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-10-31 US disclosed
US-4845254-A REMOVAL FROM FEEDSTREAM SILVER OR COPPER COMPLEXES AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-07-04 US disclosed
EP-0302436-A2 Metal-diketone absorbents for carbon monoxide or olefins AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-02-08 EP disclosed
EP-0265305-A1 5-Pyrazolone derivatives, process for their preparation, their use as herbicides and compositions containing them ROUSSEL-UCLAF (FR) 1988-04-27 EP disclosed